Human Resistin as a Marker to Monitor Lupus Nephritis and Atherosclerotic Changes in Females with SLE

Systemic lupus erythematosus (SLE) is a polygenic chronic inflammatory condition that influences several body organs. While renal and dermatological changes are among the most common presentations of disease. The current study examines possible association between human Resistin (h-Res) signs disorder activities such as inflammation, function, lipids, Bone Mineral Density (BMD) in females with SLE. We performed cross-sectional research on 50 SLE diagnosed using American College Rheumatology (ACR) criteria. Forty were recruited controls. They matched following items, including gender mass index (BMI) age. In patients, we discovered statistically significant positive relationship h-Res levels ESR, CRP, Cr, ds-DNA, C3, duration steroid treatment, other variables. Disorder activity determined by systemic disease (SLEDAI) carotid intima-media thickness (CIMT) (p-value <0.05). C3 to have negative relationship. case SLE, level can be used marker for Lupus Nephritis (LN) atherosclerosis. patients more aggressive therapy underlying process better control traditional risk factors may beneficial reducing atherosclerotic derangement. Keywords. biomarker, nephritis, erythematous, Atherosclerosis